Integrin Alpha2b antibody
Quick Overview for Integrin Alpha2b antibody (ABIN3037269)
Target
See all Integrin Alpha2b (CD41) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- The antibody IVA30 reacts with CD41/CD61 complex (bovine), one of the earliest markers of the megakaryocytic lineage. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes, the complex may be absent or strongly reduced in Glanzmann's thrombasthenia (GT).
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Purification
- Purified from ascites by protein-A affinity chromatography
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Immunogen
- Bovine trombocytes.
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Isotype
- IgG2
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 15 mM sodium azide, approx. pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- Integrin Alpha2b (CD41)
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Alternative Name
- CD41
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Pathways
- Integrin Complex
Target
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